What are the reperfusion rates after fibrinolysis compared to primary percutaneous coronary intervention in myocardial infarction with ST-segment elevation?
A: The goal of reperfusion therapy is early and complete recanalization of the infarct-related artery to salvage myocardium and improve both early and late clinical outcomes. Complete reperfusion can be achieved with either fibrinolysis or primary percutaneous coronary intervention (PCI). The success rate of primary PCI is higher than 90%, whereas current fibrinolytic therapy leads to full reperfusion in only 50 to 55% of recipients. Primary PCI, therefore, appears to be the most appropriate reperfusion tool, but there are substantial logistic restrictions associated with its use.